By Jonathan Mant, Marion F. Walker
Stroke is the commonest explanation for grownup incapacity and is of accelerating significance inside of getting older populations.
This fresh identify within the ABC sequence covers the whole sufferer trip, from prevention via to long term aid. It comprises fundamental prevention and administration of possibility elements for stroke and secondary prevention together with pharmaceutical, way of life and surgical intervention. the overall ideas of stroke rehabilitation also are addressed in addition to mobility, communique and mental difficulties, as is stroke in more youthful humans. It additionally covers long term aid for stroke survivors and their carers.
This is a useful and useful advisor to all features of stroke for either health and wellbeing care execs and lay audiences. it's of specific relevance to basic practitioners, junior medical professionals, nurses and therapists operating with stroke sufferers and their...
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Additional info for ABC of Stroke
Although epidemiological studies have not demonstrated significant associations between cholesterol and stroke risk, the strong evidence from randomised controlled trials that cholesterol lowering with statins lowers stroke risk suggests that there is a causal association. Conversely, although epidemiological studies have shown a link between raised serum homocysteine levels and risk of stroke, randomised controlled trials have not unequivocally demonstrated that lowering homocysteine (through folate supplementation) leads to reduced stroke risk.
Data Source: Office for National Statistics. Mortality statistics: Deaths registered in 2008. Review of the National Statistician on deaths in England & Wales 2008. Series DR, Crown Copyright 2009. 3. The importance of a risk factor is determined both by its frequency in the population and the strength of its association with stroke (as measured by the size of the relative risk). 3). 5-fold increase in risk Diet: obesity; low potassium; high salt; low fruit and vegetable intake Other conditions Diabetes mellitus: doubling of risk Atrial fibrillation: fivefold increase in risk Ischaemic heart disease: doubling in risk Cardiac sources of thrombo-embolism Haematological disorders: sickle cell disease; raised packed cell volume; hypercoagulability Carotid artery stenosis Migraine Genetic Positive family history in parents: 50–100% increase in risk 2 single nucleotide polymorphisms (SNPs) on choromosome 12p13 associated with 40% increase in risk Other factors Oral contraception: doubling of risk Hormone replacement therapy: doubling of risk Major life events Influenza and other intercurrent infections There is considerable overlap between the risk factors for stroke and the risk factors for ischaemic heart disease.
Hypertension: Management of hypertension in adults in primary care. NICE Clinical Guideline no 34, London 2006 Cholesterol Lowering People with raised cardiovascular risk should be offered treatment with a statin. 1. 5 mmol/l reduction in LDL cholesterol, which would reduce the risk of cardiovascular events by about a third. 3). Long-term follow-up of one of these trials, the West of Scotland Coronary Prevention Study, found that the benefits of statin therapy were sustained for 10 years after the trial ended, even though after the trial finished similar proportions of the intervention and control groups were being treated with statins.
ABC of Stroke by Jonathan Mant, Marion F. Walker